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Orthobiologics: A Safe and Effective Alternative to Steroid Injections

Orthobiologics: A Safe and Effective Alternative to Steroid Injections

The landscape of treating musculoskeletal conditions is changing as more people turn to orthobiologics for a more natural and longer-lasting alternative to steroid injections. In this blog post, we’ll explore the advantages of orthobiologics over steroid injections, such as fewer side effects and increased regenerative potential, and delve into the mechanisms of action, evidence for efficacy and safety, and the risks and limitations of each treatment approach.

How it works

When it comes to treating musculoskeletal conditions, orthobiologics, and steroid injections work differently. Orthobiologics tap into the body’s own repair processes by providing growth factors, cytokines, stem cells, or extracellular matrix. These substances help promote tissue regeneration and healing. On the other hand, steroid injections focus on suppressing inflammation and pain by blocking the production of prostaglandins and leukotrienes. Although they provide short-term relief, they don’t necessarily address the root cause of the issue. Orthobiologics have a more regenerative effect on the body, working to restore damaged tissues, while steroid injections primarily have a palliative effect, focusing on temporary pain relief.

The world of orthobiologics is filled with exciting possibilities, such as platelet-rich plasma (PRP), bone marrow concentrate, adipose-derived stem cells, and extracellular vesicles. These substances have been studied for their potential to treat various musculoskeletal conditions. Numerous studies have shown positive outcomes of orthobiologics for conditions such as osteoarthritis, tendinopathy, rotator cuff tears, and trochanteric bursitis. These treatments often result in improved function and reduced pain. Of course, there are potential risks and limitations, including infection, allergic reaction, variability in effectiveness, and cost. Nonetheless, these risks are generally considered to be low when compared to the side effects of steroid injections.

Platelet-Rich Plasma (PRP) therapy
Steroid injections, like cortisone, dexamethasone, and triamcinolone, have been commonly used to treat musculoskeletal conditions by providing short-term pain relief. Studies have demonstrated their benefits for conditions such as osteoarthritis, tendinopathy, rotator cuff tears, and trochanteric bursitis. Yet, these injections may not address the underlying issue and may have diminishing returns over time. Potential risks and limitations of steroid injections include tissue damage, infection, systemic effects, and reduced healing response. These side effects can be more significant than those associated with orthobiologics, leading to a preference for the latter in many cases.


Orthobiologics are emerging as a safe and effective alternative to steroid injections for treating musculoskeletal conditions. Stimulating the body’s natural healing processes leads to tissue regeneration and lasting relief. If you’re intrigued by the potential of orthobiologics, we encourage you to consult with your physician to determine the best course of treatment for your specific needs. Embrace the healing power of your body and explore the world of orthobiologics today!

How To Learn More About Orthobiologics

Are you ready to take the first step towards a more natural, regenerative approach to treating your musculoskeletal condition? Don’t hesitate to reach out to Dr. Sachdev, a pioneer in orthobiologic treatments at Sachdev Orthopaedics. With his expertise and dedication to cutting-edge therapies, you’ll be in the best hands possible. Call Sachdev Orthopaedics today and embark on your journey towards lasting relief and improved quality of life!

Appointment Requests

sachdev orthopaedics llc, 3735 nazareth rd, suite 302, easton, pa 18045

To make an appointment, please call (610) 515-9994

Normal Hours

Monday, Wednesday, Thursday 8:30-5 pm
Tuesday 8:30-6 pm
Friday 8:30-12 noon


Sachdev Orthopaedics LLC,
3735 Nazareth Rd, Suite 302A, Easton, PA 18045