A2M is a protein that is made by liver and found in your blood. The A2M found naturally in your blood inhibits three major proteins – Cytokines, Matrix Metalloproteinases (MMP’s), and ADAMTS Degradation Proteases that break down your cartilage, causing Osteoarthritis (OA). The protective characteristics of A2M allows this vital protein as the human body’s own defense against Osteoarthritis (OA).
A2M is a Broad-Spectrum Multi-Purpose Protease Inhibitor that captures and inactivates the bad chemicals damaging your joints and causing pain. Once these bad chemicals are trapped by the A2M, the body eliminates them through natural mechanisms.
A significant research study out of Brown University, in collaboration with the National Institute of Health, demonstrated that concentration of intra-articular A2M is insufficient for joint protection and a supplemental intra-articular injection of A2M provides chondral protection in post-traumatic OA by stopping the progression of Osteoarthritis (OA)